Independent Research in Internal Medicine

Prof. Adnan Erol is an independent researcher in internal medicine, focused on hypothesis-driven research into disease mechanisms, cellular regulation, and human health.

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Portrait of Prof. Adnan Erol, independent researcher in internal medicine

A CAREER IN INTERNAL MEDICINE.

M.D., Hacettepe University

Internal Medicine Specialist

Associate Professor

Full Professor

From clinical observation to molecular mechanisms — connecting internal medicine, biochemistry, and cellular signaling.

FROM CLINICAL QUESTIONS TO MOLECULAR MECHANISMS.

Research Interests

Prof. Adnan Erol’s research examines the molecular mechanisms underlying disorders of energy metabolism and their links to chronic disease, cancer, inflammation, and cellular adaptation.

His work integrates clinical internal medicine with molecular biology, biochemistry, and immunoregulation.

Explore Research

Research into how disturbances in cellular energy metabolism contribute to insulin resistance, metabolic disease, neurodegeneration, and malignant transformation.

Energy metabolism

Insulin resistance

Oncology

Oxidative stress

Investigation of signaling networks connecting metabolic and genotoxic stress with cellular repair, adaptation, senescence, apoptosis, and transformation.

Signal transduction

Redox regulation

Cell fate

Stress response

Study of the interactions between metabolic dysfunction, immune regulation, inflammatory signaling, and disease progression.

Immunoregulation

Inflammation

Efferocytosis

Cytokine signaling

Mechanistic interpretation of clinical observations, connecting bedside questions with molecular hypotheses and potential clinical applications.

Internal medicine

Molecular mechanisms

Translational research

SELECTED SCHOLARLY WORK.

Selected Publications

A selection of publications addressing cellular stress, metabolic dysregulation, inflammation, and disease mechanisms.

CELLULAR SIGNALING · 2022

Genotoxicity-Stimulated and CYLD-Driven Malignant Transformation

Cancer Management and Research
PMID: 35958947

IMMUNOREGULATION · 2022

Importance of Efferocytosis in COVID-19 Mortality

Infection and Drug Resistance
PMID: 35299855

REDOX BIOLOGY · 2022

IKK-mediated CYLD phosphorylation and cellular redox activity

Molecular Medicine
PMID: 35109788

METABOLISM & ONCOLOGY · 2014

Type 2 diabetes and cancer as redox diseases?

The Lancet
PMID: 25209482

FROM OBSERVATION TO MECHANISM.

Research Approach

His work begins with clinical questions and develops them through mechanistic interpretation across molecular biology, biochemistry, and immunoregulation.

1. Clinical Observation

Identify recurring patterns and unresolved questions emerging from human disease and clinical medicine.

2. Mechanistic Hypothesis

Translate clinical observations into hypotheses involving metabolism, signaling, inflammation, and cellular stress.

3. Molecular Integration

Connect evidence across biochemistry, molecular biology, immunoregulation, and disease-specific literature.

4.Translational Perspective

Evaluate how mechanistic insights may improve disease understanding and support future clinical applications.

Explore how these research themes are developed in selected publications →

ACADEMIC CONTACT.

Contact

For academic correspondence, publication-related inquiries, or research discussion, please use the email address below.

ae@adnanerol.org

Academic Profiles

Google Scholar

ResearchGate

PubMed

ORCID